Best to limit the use of gastroprotectant drugs in dogs and cats

The gastrointestinal mucosal barrier is continuously exposed to toxins, bacteria, and drugs, leading to the development of inflammatory, erosive, and eventually ulcerative lesions. Unfortunately, critical evaluation of gastroprotectant drugs in experimental models and in dogs and cats with spontaneous disease is scarce, and most studies that have evaluated their efficacy have been conducted in healthy animals. A review of 2018 signed by distinguished names in global veterinary gastroenterology offers a consensus opinion on the rational administration of gastrointestinal protectants to dogs and cats, with a focus on proton pump inhibitors...