Close this search box.

An effective nutraceutical against intestinal dysbiosis in dogs with atopic dermatitis

A nutraceutical based on black currant oil is useful in controlling intestinal dysbiosis and itching in dogs with atopic dermatitis.

Published on
, byRaffaella Daghini

In addition to the skin-level effects, which manifest as barrier impairment, itching, and lesions, atopic dermatitis causes alterations in the gut microbiome in affected dogs.

A study evaluated the effects of a nutraceutical formulation based on blackcurrant oil, Lactobacillus reuteri tindallyzed, nucleotides, and zinc oxide on the gut microbiome, fecal score, and itching assessed by the VAS scale (Visual Analogue Scale) in 45 dogs with atopic dermatitis, on maintenance therapy for at least one year.

The dogs were fed a diet of hydrolyzed chicken and rice, keeping current therapies unchanged for the duration of the study. The nutraceutical(Ribes Pet Symbio®) was administered once daily to all dogs for the first 60 days, while in the second phase of the study, also lasting 60 days, administration was discontinued.

Microbiome analyses were conducted on stool samples collected at baseline and after 60 and 120 days from the start of the study, calculating the fecal score and dysbiosis index. The SEA score was also calculated at the same times.

Statistical analysis indicates that the fecal score, dysbiosis index and VAS score improved significantly in the first 60 days. In contrast, between day 60 and day 120, that is, when nutraceutical administration was stopped, the fecal score and VAS score did not change significantly, while the dysbiosis index worsened.

The results of the study, therefore, indicate that this nutraceutical, based on black currant oil, Lactobacillus reuteri tindalus, nucleotides, and zinc oxide, is useful in controlling intestinal dysbiosis and itching in dogs with atopic dermatitis.


Cornegliani L, Persico P, Gramenzi A. Effectiveness of a nutraceutical with blackcurrant oil and tyndalised Lactobacillus reuteri in controlling intestinal dysbiosis and pruritus in atopic dogs. Veterinary Dermatology 2020;31(Suppl. 1):6-109.

Explore the latest content
30_04_2024_Microbiota, body condition score e consistenza delle feci nei gatti che vivono in rifugio
Microbiota, body condition score and stool consistency in cats living in shelters
27_02_2024_Isolamento di C. difficile in cani con problemi digestivi e antibioticoresistenza
Isolation of C. difficile in dogs with digestive problems and antibiotic resistance
20_02_2024_Il microbiota dei cani in trattamento per shunt porto-sistemico congenito
The microbiota of dogs being treated for congenital porto-systemic shunt
See more content on e
16_02_2024_Colite acuta nel cane gestione nutrizionale Vs metronidazolo
Acute colitis in the dog: nutritional management Vs metronidazole
13_02_2024_Effetti di L. Reuteri NBF 2 sul microbiota intestinale e sul benessere di gatti persiani
Effects of L. reuteri NBF 2 on the gut microbiota and well-being of Persian cats
06_02_2024_Probiotici per cani e gatti a che punto siamo
Probiotics for dogs and cats: where do we stand?
02_02_2024_Enteropatia cronica nei cani effetti di simbiotico e IgY sul microbiota intestinale
Chronic enteropathy in dogs: effects of symbiotic and IgY on gut microbiota
11_01_2024_Rapporto ufficiale EFSA sull’efficacia di Lactobacillus reuteri DSM 32203 (NBF LANES) per cani
Official EFSA report on the efficacy of Lactobacillus reuteri DSM 32203 (NBF LANES) for dogs
09_06_2023_Gestione nutrizionale e nutraceutica di pazienti felini con patologia renale cronica due casi clinici
Nutritional and nutraceutical management of feline patients with chronic kidney disease: two clinical cases
02_06_2023_Acido grasso DPA possibili impieghi nella colite istiocitaria ulcerativa
DPA fatty acid: possible uses in ulcerative histiocytic colitis
30_05_2023_Dermatite allergica alle pulci studio comparativo su due nutraceutici
Flea allergic dermatitis: comparative study of two nutraceuticals