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Attenuation of phosphorus restriction in cats with chronic kidney disease and ionized hypercalcemia

Attenuation of phosphorus restriction in cats with chronic kidney disease and ionized hypercalcemia

The cats involved in the study saw a resolution of hypercalcemia after switching to the phosphorus-reduced diet, with a lower Ca:P ratio.
Azotemic chronic kidney disease(CKD) is a common condition in older cats and is associated with alterations in calcium homeostasis in this species. In addition, hyperphosphatemia is associated with an increased risk of azotemia progression and death in cats with CKD. Dietary restriction of phosphorus may contribute to the development of hypercalcemia because lower dietary phosphates, and thus a higher calcium-to-phosphorus (Ca:P) ratio, could lead to increased intestinal absorption of calcium. The goal set by the Royal Veterinary College was to describe theeffect of feeding a moderately phosphorus-restricted diet (MP; 1.5 g/Mcal phosphorus; C...
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