Antioxidant effect of fermentative S-acetyl-glutathione and silybin in dogs with liver disease

Can a constituent of a plant like thistle have a powerful protective effect not only on the liver but also on cell barriers? A team of Italian scientists in 2023 investigated the effects of silymarin contained in milk thistle and S-acetyl-glutathione as antioxidants. The liver plays an important role in regulating the body’s antioxidant status, being the major site for the synthesis of glutathione (GSH), the main intracellular antioxidant. The important role of GSH as an antioxidant is to enable detoxification from the products of aerobic metabolism (such as superoxide, hydrogen peroxide, and toxic oxygen radicals) and to protect tissue...