Antibacterial activity of Manuka honey and its components

Manuka honey can be safely used as an alternative natural antibiotic, exerting a stimulating effect on macrophages to release mediators necessary for tissue healing and reduction of microbial infections.

Published on
, byGiulia Pignataro

In general, honey is used in our kitchens as a food ingredient, rich in specific properties, but there is also a monofloral honey, Manuka honey,which has recently been the subject of research in many scientific laboratories for its unique properties, especially its antimicrobial activity.

The reason for studying the antibacterial properties of honey is to find safe and natural antibiotics.

In this 2018 review, the authors focused specifically on Manuka honey, which could in fact be used as a natural antibiotic and as an alternative medicine.

This review provides a clear position: the importance of honey for medicinal purposes cannot be underestimated. Research data confirmed that the antibacterial activity of Manuka honey, compared with other types of honey, is due to a higher content of phenols and methylglyoxal.

Manuka honey can be safely used as an alternative natural antibiotic, exerting a stimulating effect on macrophages to release mediators necessary for tissue healing and reduction of microbial infection.Unique Manuka Factor (UMF), which depends on the methylglyoxal content, is also important for the antibacterial activity of honey.

Manuka honey also has the ability to release hydrogen peroxide, an important factor that helps reduce bacterial activity, making this honey particularly effective against resistant microorganisms such as S. aureus and P. aeruginosa.

The medicinal properties of honey derive from bioactive compounds in plant nectar that make honey a natural antimicrobial agent by allowing it to inhibit the growth of various harmful microorganisms.

This bee product, therefore, has been found to be particularly useful in wound care, treatment of burns, and in supporting the health of the immune system. In summary, Manuka honey is a natural and safe antibiotic, since no published literature reports bacterial resistance in its conflons, and this is, attributed to the complexity of the honey’s components that act both individually and synergistically with other components.

Therefore, based on these findings , it would be interesting to initiate further research evaluating the possible synergy between Manuka honey of different UMF values with commercial antibiotics to establish an alternative approach in the treatment of infections with antibiotic-resistant microorganisms.

Reference

Matthew Johnston, Michael McBride, Divakar Dahiya, Richard Owusu-Apenten and Poonam Singh Nigam. Antibacterial activity of Manuka honey and its components: An overview. AIMS Microbiology, 4(4): 655-664. DOI: 10.3934/microbiol.2018.4.655

Explore the latest content
01_04_2025_Diarrea acuta nel cane la cellulosa alimentare favorisce il recupero clinico
Acute diarrhea in dogs: dietary cellulose promotes clinical recovery
21_03_2025_Effetti della dieta vegana e a base animale sul microbiota di cani adulti sani
Effects of vegan and animal-based diet on the microbiota of healthy adult dogs
11_03_2025_Vitamine, minerali e fitonutrienti come modulatori della funzione immunitaria canina
Vitamins, minerals and phytonutrients as modulators of canine immune function
See more content on
01_04_2025_Diarrea acuta nel cane la cellulosa alimentare favorisce il recupero clinico
Acute diarrhea in dogs: dietary cellulose promotes clinical recovery
11_03_2025_Vitamine, minerali e fitonutrienti come modulatori della funzione immunitaria canina
Vitamins, minerals and phytonutrients as modulators of canine immune function
25_02_2025_Efficacia e tollerabilità dell'olio di canapa nei cani che soffrono di dolore cronico
Efficacy and tolerability of hemp oil in dogs suffering from chronic pain
18_02_2025_Dieta e nutraceutici nel cane con disfunzione cognitiva una review
Diet and nutraceuticals in dogs with cognitive dysfunction: a review
11_02_2025_Potenziali benefici del lievito Saccharomyces in cani e gatti
Potential benefits of Saccharomyces yeast in dogs and cats
04_02_2025_Effetto degli antiossidanti alimentari sul danno da radicali liberi in cani e gatti
Effect of dietary antioxidants on free radical damage in dogs and cats
28_01_2025_Attività antibatterica del miele di Manuka e dei suoi componenti
Antibacterial activity of Manuka honey and its components
21_01_2025_Gli effetti potenzianti dei polisaccaridi di liquirizia sulla salute delle vie respiratorie
The enhancing effects of licorice polysaccharides on respiratory health